Production and characterization of monoclonal antibodies against major histocompatibility complex class I chain-related gene A
โ Scribed by W. Wongsena; G. Sconocchia; H. S. Cho; C.-C. Chang; X. Wang; K. Klumkrathok; S. Ferrone; C. Leelayuwat
- Book ID
- 110892845
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 773 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0001-2815
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The polymorphic major histocompatibility complex class I-related chain A (MICA) antigen is being increasingly recognized as a potential target molecule for immune cells during allograft rejection. Here we studied whether MICA is a target antigen for antibodies in liver transplant patients. Eighty-fo
## Abstract Complexes of major histocompatibility complex (MHC) class II molecules containing invariant chain (Ii)โderived peptides, known as class IIโassociated invariant chain peptides (CLIP), are expressed at high levels in presentationโdeficient mutant cells. Expression of these complexes in mu