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Production and Characterization of Biologically Active Human GM-CSF Secreted by Genetically Modified Plant Cells

โœ Scribed by Eddie A. James; Changlin Wang; Zeping Wang; Raymond Reeves; Joong Han Shin; Nancy S. Magnuson; James M. Lee


Book ID
115645650
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
164 KB
Volume
19
Category
Article
ISSN
1046-5928

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โœ Eddie A. James; Changlin Wang; Zeping Wang; Raymond Reeves; Joong Han Shin; Nanc ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 164 KB

Human granulocyte-macrophage colony-stimulating factor (GM-CSF), a hemopoietic growth factor, was produced and secreted from tobacco cell suspensions. The GM-CSF cDNA was carried by a binary vector under the control of the CaMV 35S promoter and the T7 terminator. In addition, a 5-nontranslated regio