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Production and characterization of adeno-associated viral vectors

✍ Scribed by Grieger, Joshua C; Choi, Vivian W; Samulski, R Jude


Book ID
109945843
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
548 KB
Volume
1
Category
Article
ISSN
1750-2799

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## Abstract ## Background One of the major limitations to the use of adeno‐associated virus (AAV) vectors for gene therapy has been the difficulty in producing enough vector to supply a clinical trial. More than 20 000 roller bottles may be required to generate AAV by the traditional transient tra