T cell receptor transgenic mice recogniz
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AdrianβA. Lobito; Bingzhi Yang; MarcelaβF. Lopes; Alexei Miagkov; RobertβN. Adam
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Article
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2002
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John Wiley and Sons
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English
β 415 KB
Myasthenia gravis (MG) is an autoimmune disease caused by T cell-dependent antibody-mediated reduction of acetylcholine receptors (AChR) at the neuromuscular junction. Immunization of animals with Torpedo californica AChR (TAChR) results in an experimental model of MG. We used the variable regions o