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Production and characterisation of recombinant forms of human pulmonary surfactant protein C (SP-C): Structure and surface activity

✍ Scribed by Dunja Lukovic; Inés Plasencia; Francisco J. Taberner; Jesús Salgado; Juan J. Calvete; Jesús Pérez-Gil; Ismael Mingarro


Book ID
116274190
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
521 KB
Volume
1758
Category
Article
ISSN
0005-2736

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An efficient synthesis for human-identical lung surfactant protein SP-C is described with a semi-automated solid phase synthesizer using Fmoc chemistry. Double coupling and acetic anhydride capping procedures were employed for synthetic cycles within the highly hydrophobic C-terminal domain of SP-C.