Buchbesprechungen 699 voll erscheint die Darstellung der Methodik zur Synchronisation von Hefen, insbesondere mittels der in letzter Zeit sehr verbreiteten Methode der Blockierung des Zellzyklus durch den a-bzw. a-Faktor. Von groIjem Wert sind dabei nicht nur die Darstellung der Methodik, sondern au
Product life cycle patterns for pharmaceuticals and their impact on R&D profitability of late mover products
โ Scribed by Hans H. Bauer; Marc Fischer
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 171 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0969-5931
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โฆ Synopsis
This study describes a cross-sectional and time series analysis of sales data over one decade in four major segments of the market for cardiovascular drugs. We estimate over 200 product life cycles (PLC) using a very flexible mathematical model to account for a variety of PLC shapes. Life cycles are then clustered on the basis of estimated regression coefficients. As a result this analysis leads to the detection of an international PLC classification. Moreover, it turns out that the order of entry is not only crucial to achieve a certain market share level but also to the shape of the drug life cycle and therefore for the long-term economic evaluation of innovative products. The paper provides the initial findings on this subject through a simulation study which is in line with previous research designs and shows the impact of the PLC shape on the net present value (NPV).
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