Product inhibition in a nonmotile mutant of Clostridium acetobutylicum
β Scribed by Noemi A. Gutierrez; Ian S. Maddox
- Book ID
- 103524192
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 522 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0141-0229
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Two metabolic engineering tools, namely gene inactivation and gene overexpression, were employed to examine the effects of two genetic modifications on the fermentation characteristics of Clostridium acetobutylicum. Inactivation of the butyrate kinase gene (buk) was examined using strain PJC4BK, whi
The concurrent production of acids and solvents and the production of acetone during continuous culture in a product-limited chemostat indicated that the culture contained a mixture of acid-and solvent-producing cells. Periodic oscillations in the yield of end products and the specific growth rate o