✦ LIBER ✦

Prodrugs of 2′,3′-didehydro-3′-deoxythymidine

✍ Scribed by Tetsuya Hasegawa; Toshinobu Seki; Kazuhiko Juni; Mineo Saneyoshi; Takeo Kawaguchi

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 558 KB
Volume: 82
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600821210

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Prodrugs of 2′,3′-didehydro-3′-deoxythym

Prodrugs of 2′,3′-didehydro-3′-deoxythymidine (D4T): Synthesis, antiviral activity, and rapid pharmacokinetic evaluation

✍ David R. Tortolani; John W. Russell; Valerie J. Whiterock; Michael J. M. Hitchco 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 658 KB

Synthesis and anti-HIV Activity of 4′-Cy

Synthesis and anti-HIV Activity of 4′-Cyano-2′,3′-didehydro-3′-deoxythymidine.

✍ Kazuhiro Haraguchi; Yoshiharu Itoh; Shingo Takeda; Yosuke Honma; Hiromichi Tanak 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 22 KB 👁 2 views

ChemInform Abstract: Synthesis and Antit

ChemInform Abstract: Synthesis and Antitumor Activity of 2′,3′-Didehydro-3′-deoxythymidine and Its Derivatives.

✍ B.-H. LEE; M.-K. LIM; J.-H. SHIN; T.-S. JANG; J.-S. PARK; S.-W. KANG 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Ester Derivatives of Nucleoside Inhibito

Ester Derivatives of Nucleoside Inhibitors of Reverse Transcriptase. Part 2. Molecular Systems for the Combined Therapy with 3′-Azido-3′-deoxythymidine and 2′,3′-Didehydro-3′-deoxythymidine

✍ Yu. V. Berezovskaya; M. V. Chudinov 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 18 KB

Synthesis of 2′,3′-Disubstituted 3′-Deox

Synthesis of 2′,3′-Disubstituted 3′-Deoxythymidine Derivatives

✍ P. Herdewijn; A. van Aerschot 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) ⚖ 276 KB 👁 1 views

Synthesis of 2′-Azido-2′,3′-didehydro-2′

Synthesis of 2′-Azido-2′,3′-didehydro-2′,3′-dideoxythymidine

✍ Mikhailopulo, Igor A. ;Zaitseva, Galina V. ;Vaaks, Elena V. ;Balzarini, Jan ;De 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 598 KB

## Abstract Compound 15 – the 2′‐azido analog of the anti‐HIV compound 2′,3′‐didehydro‐2′,3′‐dideoxythymidine – was synthesized. Treatment of 5′‐__O__‐trityl‐β‐D‐ribofuranosylthymine (1) with DAST or MSTF gave the 2,2′‐anhydro derivative 2. The latter and its 3′‐__O__‐benzoate 3 were used for the s