Diastereotopic selection of C2 hydrogens
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J.M. Coxon; D.Q. McDonald
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Article
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1988
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Elsevier Science
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French
โ 165 KB
Rearrangement of styrene oxide with (a) LiC104 and (b) BF3 to give phenylethanal exhibits diastereotopic selection with migration of the hydrogen trans to the phenyl group being favoured 1.4 and 1.14 times respectively. The rate of rotation about the Cl -C2 bond of the intermediate is comparable, bu