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Processing and analysis of CASP3 protein structure predictions

✍ Scribed by Adam Zemla; Česlovas Venclovas; John Moult; Krzysztof Fidelis

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
316 KB
Volume
37
Category
Article
ISSN
0887-3585

No coin nor oath required. For personal study only.

✦ Synopsis

Livermore Prediction Center provides basic infrastructure for the CASP (Critical Assessment of Structure Prediction) experiments, including prediction processing and verification servers, a system of prediction evaluation tools, and interactive numerical and graphical displays.

Here we outline the essentials of our approach, with discussion of the superposition procedures, definitions of basic measures, and descriptions of new methods developed to analyze predictions. Our primary focus is on the evaluation of threedimensional models and secondary structure predictions. To put the results of the three prediction experiments held to date on the same footing, the latest CASP3 evaluation criteria were retrospectively applied to both CASP1 and CASP2 predictions. Finally, we give an overview of our website (http://PredictionCenter.llnl.gov), which makes the target structures, predictions, and the evaluation system accessible to the community.

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