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Process Optimization of a Complex Pharmaceutical Polymorphic System via In Situ Raman Spectroscopy

✍ Scribed by Starbuck, Cindy; Spartalis, Angela; Wai, Lawrence; Wang, Jian; Fernandez, Paul; Lindemann, Christopher M.; Zhou, George X.; Ge, Zhihong

Book ID
120459897
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
294 KB
Volume
2
Category
Article
ISSN
1528-7483

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In situ study on kinetic behavior during asymmetric membrane formation via phase inversion process using Raman spectroscopy
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Asymmetric membrane formation has been studied by using an in situ analysis developed with a Micro Raman spectroscopy, which emphasizes kinetic aspects of the phase inversion process. Changes in composition with time was successfully measured on the gelation bath-side as well as inside the precipita