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Proceedings: A comparison of the cell killing in the mouse after exposure to ftorafur and to 5-fluorouracil

✍ Scribed by Van Putten, L M; Kram-Idsenga, L K; Pijpers-de Bruin, M

Book ID
109833277
Publisher
Nature Publishing Group
Year
1974
Tongue
English
Weight
343 KB
Volume
30
Category
Article
ISSN
0007-0920

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## Abstract Defects in apoptosis have been implicated in chemoresistance of colon cancer cells. We report here the ability to resist to 5‐fluorouracil‐induced apoptosis of 8 colon cancer cell lines differing in __p53__ and __bax__ status: p53^βˆ’/0^bax^+/+^ for TC7, SW480, HT‐29; p53^+/+^bax^βˆ’/βˆ’^ for