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Procedure for isolation of neuron- and astrocyte-enriched fractions from chick brain of different ages

✍ Scribed by B. Usha Rani; N. Indrapal Singh; A. Ray; Professor K. Subba Rao


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
303 KB
Volume
10
Category
Article
ISSN
0360-4012

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✦ Synopsis


A method for the isolation of ncurons and astrocytes from chick brain of different ages is described. In bricf. the procedure involves incubation of the gray matter with trypsin, passage of the tissue successively through nylon'stainless steel screens of decreasing pore size, and further separation and purification of cell-enriched fractions by centrifugation on Ficoll discontinuous gradient. Phase-contrast microscopy revealed intact morphology of the cells. The cells were viable by trypan blue exclusion test.