Scale up of a viscous fungal fermentatio
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D.J. Pollard; T.F. Kirschner; G.R. Hunt; I.-T. Tong; R. Stieber; P.M. Salmon
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Article
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2006
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John Wiley and Sons
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English
β 404 KB
π 1 views
## Abstract The scale up of the novel, pharmaceutically important pneumocandin (B~0~), from the filamentous fungus __Glarea lozoyensis__ was successfully completed from pilot scale (0.07, 0.8, and 19 m^3^) to production scale (57 m^3^). This was accomplished, despite dissimilar reactor geometry, em