𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Problems And Paradigms: Metaphors and the role of genes in development

✍ Scribed by H. F. Nijhout

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
791 KB
Volume
12
Category
Article
ISSN
0265-9247

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

In describing the flawless regularity of developmental processes and the correlation between changes at certain genetic loci and changes in morphology, biologists frequently employ two metaphors: that genes β€˜control’ development, and that genomes embody β€˜programs’ for development. Although these metaphors have an admirable sharpness and punch, they lead, when taken literally, to highly distorted pictures of developmental processes. A more balanced, and useful, view of the role of genes in development is that they act as suppliers of the material needs of development and, in some instances, as context‐dependent catalysts of cellular changes, rather than as β€˜controllers’ of developmental progress and direction. The consequences of adopting this alternative view of development are discussed.

πŸ“œ SIMILAR VOLUMES

Problems and paradigms: Hoemeobox genes
Problems and paradigms: Hoemeobox genes in vertebrate evolution
✍ Peter Holland πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 936 KB

## Abstract A wide range of anatomical features are shared by all vertebrates, but absent in our closest invertebrate relatives. The origin of vertebrate embryogenesis must have involved the evolution of new regulatory pathways to control the development of new features, but how did this occur? Mut

Problems and paradigms: Redundancies, de
Problems and paradigms: Redundancies, development and the flow of information
✍ Diethard Tautz πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 519 KB

There is increasing evidence for the wide-spread existence of functionally redundant genetic pathways in developmental processes. However, both their significance and manner of evolution are still matters of debate. I will argue here that redundancy of gene actions may, in fact, be a necessary requi

Problems and paradigms: Domains, compart
Problems and paradigms: Domains, compartments and determinative switches in Drosophila development
✍ D. Gubb πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 671 KB

In BioEssays, vol. I. no. 5, p . 227, P. A . Lawrence discussed the selector gene hypothesis and its implications for development. In the following article, D. Gubb presents an alternative view of the genetic control of development. I ! "If you don't love me why are you fertilizing my eggs?"