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Probing the Structural and Dynamic Properties of KCNE1 using Site-Directed Spin Labeling EPR Spectroscopy

โœ Scribed by Troxel, Kaylee R.; Sahu, Indra D.; Coey, Aaron T.; Swartz, Max S.; Hawn, Jaclyn M.; Gunasekera, Thusitha S.; McCarrick, Robert M.; Welch, Richard C.; Vanoye, Carlos G.; Kang, Congbao; Sanders, Charles R.; Lorigan, Gary A.

Book ID
122243308
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
40 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract EPR spectroscopy is a technique that specifically detects unpaired electrons. EPRโ€sensitive reporter groups (spin labels or spin probes) can be introduced into biological systems via siteโ€directed spinโ€labeling (SDSL). The basic strategy of SDSL involves the introduction of a paramagnet