## Abstract This paper reports a specific reaction parameter (SRP) PM3/d model for iron that can reproduce the DFT/MM results of the hydrogen abstraction reaction from the C11 position of linoleic acid by the Soybean lipoxygenaseβ1 enzyme. A suite of nonlinear optimization methods is outlined for s
Probing the role of the iron in soybean lipoxygenase-1
β Scribed by MarkJ. Nelson
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 77 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0162-0134
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Lipoxygenases (LOXs) form a heterogeneous family of lipid-peroxidizing enzymes, and several LOX-isoforms (12/15-LOX, 5-LOX) have been implicated in atherogenesis. However, the precise role of these enzymes is still a matter of discussion. 12/15-LOXs are capable of oxidizing lipoproteins (low-density
The interaction of furan fatty acids (F-acids) with lipoxygenase was investigated by incubation experiments of a synthetic dialkyl-substituted F-acid with soybean lipoxygenase-1. Originally the oxidation of furan fatty acids was assumed to be directly effected by lipoxygenase. It is now demonstrated