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Probing the Escherichia coli transcriptional activator MarA using alanine-scanning mutagenesis: residues important for DNA binding and activation

โœ Scribed by William K. Gillette; Robert G. Martin; Judah L. Rosner


Book ID
115630296
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
314 KB
Volume
299
Category
Article
ISSN
0022-2836

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โœ Christine Edmead; Chryso Kanthou; Omar Benzakour ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 120 KB

Thrombin, a serine protease, is an important effector of many cellular processes and has been shown to upregulate the expression of several genes. The mechanisms underlying thrombin-mediated regulation of gene transcription remain poorly understood. The original aim of this work was to study the eff