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Probing the dynamics of prion diseases with amphotericin B

✍ Scribed by Karim Tarik Adjou; Jean-Philippe Deslys; Rémi Demaimay; Dominique Dormont

Book ID
117680590
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
543 KB
Volume
5
Category
Article
ISSN
0966-842X

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A salient characteristic of the prion diseases--including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy in cattle--is an extended asymptomatic incubation period followed by a rapid and often fatal clinical phase. We present a kinetic model of progression of infection based upon the