✦ LIBER ✦

Probing the Binding of Indolactam-V to Protein Kinase C through Site-Directed Mutagenesis and Computational Docking Simulations

✍ Scribed by Wang, Shaomeng; Liu, Ming; Lewin, Nancy E.; Lorenzo, Patricia S.; Bhattacharrya, Dipak; Qiao, Lixin; Kozikowski, Alan P.; Blumberg, Peter M.

Book ID: 127084647
Publisher: American Chemical Society
Year: 1999
Tongue: English
Weight: 153 KB
Volume: 42
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm990129n

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Structural Basis of Binding of High-Affi

Structural Basis of Binding of High-Affinity Ligands to Protein Kinase C: Prediction of the Binding Modes through a New Molecular Dynamics Method and Evaluation by Site-Directed Mutagenesis

✍ Pak, Youngshang; Enyedy, Istvan J.; Varady, Judith; Kung, Justin W.; Lorenzo, Pa 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 419 KB

Probing the activation of protein C by t

Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling

✍ Karin E. Knobe; Ann Berntsdotter; Lei Shen; John Morser; Björn Dahlbäck; Bruno O 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 647 KB

Protein C (PC) is activated to an essential anticoagulant enzyme (activated PC or APC) by thrombin (T) bound to thrombomodulin (TM), a membrane receptor present on the surface of endothelial cells. The understanding of this complex biological system is in part limited due to the lack of integration

ChemInform Abstract: Structural Basis of

ChemInform Abstract: Structural Basis of Binding of High-Affinity Ligands to Protein Kinase C: Prediction of the Binding Modes Through a New Molecular Dynamics Method and Evaluation by Site-Directed Mutagenesis.

✍ Youngshang Pak; Istvan J. Enyedy; Judith Varady; Justin W. Kung; Patricia S. Lor 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 2 views

Clarification of the Binding Mode of Tel

Clarification of the Binding Mode of Teleocidin and Benzolactams to the Cys2 Domain of Protein Kinase Cδ by Synthesis of Hydrophobically Modified, Teleocidin-Mimicking Benzolactams and Computational Docking Simulation

✍ Endo, Yasuyuki; Takehana, Shunji; Ohno, Michihiro; Driedger, Paul E.; Stabel, Si 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 505 KB