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Probing Receptor-Translocator Interactions in the Oligopeptide ABC Transporter by Fluorescence Correlation Spectroscopy

✍ Scribed by Doeven, Mark K.; van den Bogaart, Geert; Krasnikov, Victor; Poolman, Bert


Book ID
119921596
Publisher
Biophysical Society
Year
2008
Tongue
English
Weight
402 KB
Volume
94
Category
Article
ISSN
0006-3495

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Receptor binding studies with the conventional method require the use of radioactively labelled ligands and include several washing steps. In certain cases, the halflife of the receptor-ligand complex is often shorter or similar to the time required for separation. Interactions between certain ligan