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Probing protein–chromophore interactions in Cph1 phytochrome by mutagenesis

✍ Scribed by Janina Hahn; Holger M. Strauss; Frank T. Landgraf; Hortensia Faus Gimenèz; Günter Lochnit; Peter Schmieder; Jon Hughes


Book ID
111310467
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
869 KB
Volume
273
Category
Article
ISSN
1432-1327

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Rat aldose reductase-like protein (AKR1B14) is the ortholog of mouse vas deferens protein (AKR1B7) playing roles in detoxification of reactive aldehydes and synthesis of prostaglandin F 2a . The crystal structure of the binary complex (AKR1B14-NADPH) was determined at 1.86 Å resolution, and showed t