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Probing Interaction Requirements in PTP1B Inhibitors: A Comparative Molecular Dynamics Study

✍ Scribed by Kumar, Rajendra; Shinde, Ranajit Nivrutti; Ajay, Dara; Sobhia, M. Elizabeth


Book ID
118123423
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
518 KB
Volume
50
Category
Article
ISSN
0095-2338

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Extensive proton magnetic resonance experiments were carried out on three bradykinin peptide antagonists B-9430, B-9436, and B-9858 in aqueous solutions as well as in sodium dodecylsulphate micelles (B-9430 and B-9436) and CD 3 OH/H 2 O (60%/40%) mixtures for B-9858. All three peptides showed no obs