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Probing Dynein and Kinesin Stepping with Mechanical Manipulation in a Living Cell

✍ Scribed by Peter A. Sims; X. Sunney Xie

Book ID
102123627
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
475 KB
Volume
10
Category
Article
ISSN
1439-4235

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## Abstract Cytoplasmic dynein 1 is a multi‐subunit motor protein responsible for microtubule minus end‐directed transport in axons. The cytoplasmic dynein intermediate chain subunit has a scaffold‐like role in the dynein complex; it directly binds to four of the other five subunits, the heavy chai