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Probes for narcotic receptor mediated phenomena. 46. N-substituted-2,3,4,9,10,10a-hexahydro-1H-1,4a-(epiminoethano)phenanthren-6- and 8-ols – Carbocyclic relatives of f-oxide-bridged phenylmorphans

✍ Scribed by Li, Fuying; Deck, Jason A.; Dersch, Christina M.; Rothman, Richard B.; Deschamps, Jeffrey R.; Jacobson, Arthur E.; Rice, Kenner C.

Book ID
118065885
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
879 KB
Volume
58
Category
Article
ISSN
0223-5234

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## Abstract The synthesis of a series of epoxy 5‐phenylmorphans is being explored in order to determine the conformational requirements of the phenolic ring in a phenylmorphan molecule that may be needed both for binding to a specific opioid receptor and for exhibiting opioid agonist or antagonist