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PROBABLE IDENTIFICATION OF AN HL-A SECOND-LOCUS ANTIGEN ASSOCIATED WITH A HIGH RISK OF NASOPHARYNGEAL CARCINOMA

✍ Scribed by Simons, M.J.; Wee, G.B.; Chan, S.H.; Shanmugaratnam, K.; Day, N.E.; De Thé, G.B.

Book ID
124102956
Publisher
The Lancet
Year
1975
Tongue
English
Weight
246 KB
Volume
305
Category
Article
ISSN
0140-6736

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## Abstract Methylenetetrahydrofolate reductase (MTHFR) plays a central role in converting folate to a compound which serves as a methyl donor for DNA methylation, an epigenetic modification known to be dysregulated in carcinogenesis. This case–control study assessed the contribution of __MTHFR__ p