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Probability of internal unwinding in the triple helix of collagen

✍ Scribed by Martin Schwarz Jr.; Douglas Poland


Publisher
Wiley (John Wiley & Sons)
Year
1974
Tongue
English
Weight
414 KB
Volume
13
Category
Article
ISSN
0006-3525

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✦ Synopsis


Abstract

Helix probability profiles are calculated for collagen models that take into account specific sequence and unwinding from the ends, by internal loops and by chain dissociation, using parameters from a previous study and the technique of the previous paper.^2^ An analysis is made of the occurrence of imino acids in known collagen sequences and no significant difference is found from random occurrence. Studies of model sequences generated by random placement of the imino acids show no tendency for collagen to unwind via internal loops even when one end is covalently linked and a loop is permanently nucleated at that end.


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