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Pro-apoptotic protein BIM in apoptosis of glucocorticoid-sensitive and -resistant acute lymphoblastic leukemia CEM cells

✍ Scribed by Ya-ning Zhao; Xia Guo; Zhi-gui Ma; Ling Gu; Jiao Ge; Qiang Li

Book ID: 107577256
Publisher: Springer US
Year: 2010
Tongue: English
Weight: 655 KB
Volume: 28
Category: Article
ISSN: 1357-0560
DOI: 10.1007/s12032-010-9641-x

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## BACKGROUND. Previously, the authors reported that specific antisense suppression of overexpressed proline-directed protein kinase (PDPK) F A enhances the chemosensitivity of various clinical anticancer drugs up to Ͼ 100-fold in human prostate carcinoma cells, suggesting an association of PDPK F