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Pro-apoptotic properties of parthenin analogs: a quantitative structure–activity relationship study

✍ Scribed by Rukmankesh Mehra, Amit Nargotra, Bhahwal A. Shah…


Book ID
120908596
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
528 KB
Volume
22
Category
Article
ISSN
1054-2523

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N-tert-Butyl-N,N@-dibenzoylhydrazines such as tebufenozide (RH-5992) mimic the action of a molting hormone, 20-hydroxyecdysone, and cause premature molting of larvae leading to their death. Previously, it was shown that one of the benzoyl moieties in dibenzoylhydrazines plays a role similar to that