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Pristane-induced effects on cytochrome P-4501A, ornithine decarboxylase and putrescine in rats

✍ Scribed by Carolyn M. Harper; Madhusudan G. Soni; Harihara M. Mehendale; Marvin A. Cuchens

Book ID
116123285
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
946 KB
Volume
95
Category
Article
ISSN
0304-3835

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✍ M. Reeben; J. Arbatova; J. Palgi; R. Miettinen; M. HalmekytΓΆ; L. Alhonen; J. JΓ€n πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 749 KB

Transgenic mice overexpressing ornithine decarboxylase (ODC) were recently generated (Halmekyto et al.: Biochem Biophys Res Commun 180:262-267, 1991). The dramatic ODC overexpression resulted in a very high accumulation of the polyamine putrescine in the brain. As elevated polyamine levels in the br