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Prion protein modifies TGF-β induced signal transduction

✍ Scribed by Susanne Wurm; Christian Wechselberger

Book ID: 116293540
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 488 KB
Volume: 349
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2006.08.074

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## Abstract TGF‐β1 induces cell cycle activation in mouse embryonic fibroblasts by down regulation of p27^Kip1^ but it can also induce delay of EGF‐induced cell cycle activation in these cells under similar conditions. In an attempt to determine the basis for these responses, the study of early TGF