An experimental simulation environment suitable for exploring the neuroinflammatory hypothesis of Alzheimer's disease (AD) has been developed. Using scientific literature, we have calculated parameters and rates and constructed an interactive model system. The simulation can be manipulated to explor
Prion protein expression in senile plaques in Alzheimer's disease
✍ Scribed by I. Ferrer; R. Blanco; M. Carmona; B. Puig; R. Ribera; M. J. Rey; T. Ribalta
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 229 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0001-6322
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The sequestration of RNA in Alzheimer's disease (AD) senile plaques (SPs) and the production of intraneuronal amyloid- peptides (A) prompted analysis of the mRNA profile in single immunocytochemically identified SPs in sections of AD hippocampus. By using amplified RNA expression profiling, polyme
## Abstract Alzheimer's disease (AD) and prion disease are characterized neuropathologically by extracellular deposits of Aβ and PrP amyloid fibrils, respectively. In both disorders, these cerebral amyloid deposits are co‐localized with a broad variety of inflammation‐related proteins (complement f