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Prion-induced neurodegeneration in organotypic brain slice cultures

โœ Scribed by Jeppe Falsig


Book ID
118465568
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
41 KB
Volume
5
Category
Article
ISSN
1552-5260

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We have examined the functional characteristics of microglia in an environment where the cytoarchitecture of the brain is preserved. Using organotypic slice culture under serum-free conditions, microglia initially demonstrated a rounded morphology but after 10 days in vitro (DIV), microglia in the s