Prins cyclization of 4-allyl-1,3-dioxanes prepared from 1,3-diol synthons. A rapid entry into functionalized tetrahydropyrans

✍ Scribed by Yueqing Hu; Donald J Skalitzky; Scott D Rychnovsky

• Book ID: 104255805
• Publisher: Elsevier Science
• Year: 1996
• Tongue: French
• Weight: 207 KB
• Volume: 37
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(96)02008-4

✦ Synopsis

A variety of 4-allyl-1,3-dioxanes were prepared and cyclized to give 4-chloro or 4acetoxy tetrahydropyrans in good yields and with high stereoselectivity.