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Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes

✍ Scribed by Jason S. Lamoureux; J.N. Mark Glover


Book ID
113918599
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
489 KB
Volume
14
Category
Article
ISSN
0969-2126

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This paper considers how enzymes that catalyze reactions at specific DNA sites have been engineered to overcome the problem of competitive inhibition by excess nonspecific binding sites on DNA. The formation of a specific protein-DNA recognition complex is discussed from both structural and thermody