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Principles of Peripheral Blood Mononuclear Cell Apheresis in a Preclinical Canine Model of Hematopoietic Cell Transplantation

✍ Scribed by M. Lupu; T. Gooley; E. Zellmer; S.S. Graves; R. Storb


Book ID
118094572
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
150 KB
Volume
22
Category
Article
ISSN
0891-6640

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## Abstract ## Background Conventional gene‐therapy applications of hematopoietic stem cells (HSCs) involve purification of CD34+ progenitor cells from the mobilized peripheral blood, __ex vivo__ transduction of the gene of interest into them, and reinfusion of the transduced CD34+ progenitor cell