✦ LIBER ✦
Principal component regression analysis applied in structure-activity relationships. 2. flexible opioids with unusually high safety margin
✍ Scribed by Peter P. Mager
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 387 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0323-3847
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Multicollinearities among chemical regressor variables in structure‐activity relationships can be avoided using the principal component regression analysis. An example adapted from drug design (conformationally flexible opioids) shows the working technique.