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Principal Component Analysis of the Conformational Freedom within the EF-Hand Superfamily

✍ Scribed by Babini, Elena; Bertini, Ivano; Capozzi, Francesco; Luchinat, Claudio; Quattrone, Alessandro; Turano, Maria


Book ID
126477926
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
462 KB
Volume
4
Category
Article
ISSN
1535-3893

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The EF-hand motif, which assumes a helix-loop-helix structure normally responsible for Ca 2Ο© binding, is found in a large number of functionally diverse Ca 2Ο© binding proteins collectively known as the EF-hand protein superfamily. In many superfamily members, Ca 2Ο© binding induces a conformational c