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Priming of T cells by exogenous antigen cross-presented on MHC class I molecules

✍ Scribed by Lianjun Shen; Kenneth L Rock


Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
293 KB
Volume
18
Category
Article
ISSN
0952-7915

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✦ Synopsis


Priming of T cells by exogenous antigen cross-presented on MHC class I molecules


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## Abstract SSX2 is a member of the family of cancer/testis antigens. The SSX2 derived peptide SSX2~103–111~ has been shown to be presented to cytotoxic T‐lymphocytes (CTL) by Major‐Histocompatibility (MHC) Class‐I complexes after endogenous processing, more precisely by the allele HLA‐A\*0201. The