## Abstract ## Background Interferons (IFNs) play an important role in host antiviral responses, but viruses, including vaccinia viruses (VV), employ mechanisms to disrupt IFN activities, and these viral mechanisms are often associated with their virulence. Here, we explore an attenuation strategy
β¦ LIBER β¦
Primary vaccination with an attenuated strain of vaccinia virus
β Scribed by J. van der Noordaa; F. Dekking; J. Posthuma; B. J. W. Beunders
- Publisher
- Springer Vienna
- Year
- 1967
- Tongue
- English
- Weight
- 270 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1432-8798
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## Abstract Two groups of 3 rabbits each were immunized with either recombinant vaccinia virus, WRβSFB5env, carrying the human Tβcell lymphotropic virus type I (HTLVβ1) __env__ gene at the site of the hemagglutinin gene of the WR strain, or control vaccinia virus, HAβWR, lacking the functional hema