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Primary T-cell responses induced by B7-transfected keratinocytes

✍ Scribed by Henny G. Otten; Caroline Ververs; Gijsbert C. de Gast

Book ID
103586284
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
158 KB
Volume
17
Category
Article
ISSN
0167-5699

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## Abstract As a means to increase the immunogenicity of tumor cells, we have developed a retroviral vector to transfect human B7, a molecule capable of delivering co‐stimulatory signals to T cells. Three different tumors, a melanoma, an ovarian carcinoma and a myelomonocytic leukemia, were transfe