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Primary sclerosing cholangitis, chronic ulcerative colitis, and bile duct dysplasia—Case presentation

✍ Scribed by K.V. Narayanan Menon


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
68 KB
Volume
12
Category
Article
ISSN
1527-6465

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✦ Synopsis


A 54-year-old man presented with worsening jaundice of 4 weeks' duration. He had a history of ulcerative colitis for 20 years, which was currently in remission. He was well until 4 weeks before he sought treatment from his local physician because he had noticed increasing jaundice and pruritus. He has had no fevers or chills. He has noticed a 10-to 15-pound weight loss over the past 2-3 months. His appetite had been good.


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## Background: Controversy persists regarding primary sclerosing cholangitis (psc) as a risk factor for colorectal carcinoma in patients with chronic ulcerative colitis. small sample size and differing endpoints have contributed to variation among reported studies. this large case-control study was