Primary mediastinal large cell lymphoma PMLCL is a recently described entity which has provoked considerable interest lately. The unique immunophenotype of the malignant cell, as well as conflicting reports regarding its response to therapy, prompted us to review the current literature focusing on t
Primary pulmonary large B-cell lymphoma—mediastinal type?
✍ Scribed by Gang Chen; Anthony PC Yim; Lily Ma; Philippe Gaulard; John KC Chan
- Book ID
- 108781005
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 818 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0309-0167
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## Abstract Primary mediastinal B‐cell lymphoma (PMBCL) is a sub‐type of the heterogeneous diffuse large B‐cell lymphoma category, and comprises approximately 5% of all non‐Hodgkin's lymphomas (NHL). It was first recognized as a distinct clinico‐pathologic entity 20 years ago, and recent work has f
## Abstract To address the possible genetic relationship between primary mediastinal large‐B‐cell lymphoma (PMLBCL) and diffuse large‐B‐cell lymphoma (DLBCL), we compared DNA copy number changes identified by comparative genomic hybridization (CGH) analysis of 40 PMLBCL and 91 DLBCL tumors. We asse