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Primary Ovarian Cancer Cultures are Resistant to Fas-Mediated Apoptosis

✍ Scribed by Rae Lynn Baldwin; Hang Tran; Beth Y. Karlan

Book ID: 112247773
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 95 KB
Volume: 74
Category: Article
ISSN: 0090-8258
DOI: 10.1006/gyno.1999.5448

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## Abstract Molecular mechanisms responsible for tumor resistance to apoptosis often involve the Fas/FasL pathway. While squamous cell carcinomas of the head and neck (SCCHN) express both Fas and FasL, their resistance to self‐induced apoptosis or apoptosis mediated by Fas agonistic antibody (CH‐11