Primary microcephaly in two children born to mothers with complicated appendicitis or late appendectomy during pregnancy
✍ Scribed by Nándor Ács; Ferenc Bánhidy; Andrew E. Czeizel
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 50 KB
- Volume
- 85
- Category
- Article
- ISSN
- 1542-0752
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
BACKGROUND: The possible association between maternal appendicitis/appendectomy during pregnancy and congenital abnormalities in the offspring was studied. CASES: Two cases with primary microcephaly were born to mothers who had complicated appendicitis owing to the delay of appendectomy resulting in abscess/peritonitis associated with septicemia and fever in the second trimester of pregnancy. CONCLUSIONS: Delay in surgical intervention of appendicitis in pregnancy can result in maternal morbidity that may be associated with primary microcephaly in the offspring. Birth Defects Research (Part A), 2009. © 2009 Wiley‐Liss, Inc.