Primary lymphoma of the mandible

✍ Scribed by Robbins, K. T. ;Fuller, L. M. ;Manning, J. ;Goepfert, H. ;Velasquez, W. S. ;Sullivan, M. P. ;Finkelstein, J. B.

• Publisher: Wiley (John Wiley & Sons)
• Year: 1986
• Weight: 691 KB
• Volume: 8
• Category: Article
• ISSN: 0148-6403
• DOI: 10.1002/hed.2890080311

✦ Synopsis

The mandible is an uncommon presentation site for lymphoma and misdiagnosis is common. Eleven patients with lymphoma of the mandible were seen between 1947 and 1983. In 5 of the 11 patients, the diagnosis of lymphoma could not be established from the initial biopsy and additional material for examination was required. In three patients, this resulted in a partial or total removal of the mandible. In a recent histopathologic review, the diagnosis of diffuse large cell was made in seven, diffuse undifferentiated (non-Burkitt's) in two, diffuse undifferentiated (Burkitt's) in one, and unclassified in one. Using the Ann Arbor method of staging, six patients were determined to have stage IE disease; three had stage IIE, and two had stage IV. In 10 patients definitive treatment consisted of radiotherapy, chemotherapy, or a combination of both. Treatment was limited to surgery in one patient. The 5-year overall and disease-free survival rates were 62% and 50%, respectively. These results are comparable to those for lymphoma of other extranodal head and neck sites.