Primary human herpesvirus-6 associated with an afebrile seizure in a 3-week-old infant
✍ Scribed by Danielle M. Zerr; Laurence C. Yeung; Rose Mary Obrigewitch; Meei-Li Huang; Lisa M. Frenkel; Lawrence Corey
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 74 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0146-6615
- DOI
- 10.1002/jmv.2156
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
We describe a 3‐week‐old male infant with an afebrile seizure in whom serologic and polymerase chain reaction (PCR) findings support concomitant primary human herpesvirus 6 (HHV‐6) infection. Although HHV‐6 infection has been associated with first‐time febrile seizures and encephalitis in both immunocompetent and immunocompromised hosts, it has not been associated previously with afebrile seizures in healthy infants. This report provides additional evidence of the neuropathogenic potential of HHV‐6. J. Med. Virol. 66:384‐387, 2002. © 2002 Wiley‐Liss, Inc.