𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Primary hepatocellular carcinoma and hepatitis B virus infection in korea

✍ Scribed by Whan Kook Chung; Hee Sik Sun; Doo Ho Park; Gerald Y. Minuk; Jay H. Hoofnagle

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
370 KB
Volume
11
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

Serological evidence of hepatitis B virus (HBV) infection and serum alphafetoprotein (AFP) were assayed in sera from 112 Korean patients with primary hepatocellular carcinoma (PHC) and from 63 age- and sex-matched controls. Serological evidence of HBV infection was found in 100% of PHC patients and in 97% of controls. The majority of PHC patients (87%) were positive for hepatitis B surface antigen (HBsAg). In contrast, only 14% of control individuals were positive for HBsAg, but 82% were positive for antibody to HBsAg (anti-HBs). Hepatitis B e antigen (HBeAg) was detected in a high percentage (38%) of HBsAg-positive PHC patients, but in none of the nine HBsAg-positive control individuals. Serum AFP was detectable in 83% of PHC patients but in only one of 63 controls (1.5%). These results document that HBV infection may be the major factor in the development of PHC in this country.

πŸ“œ SIMILAR VOLUMES

Hepatitis B virus and primary hepatocell
Hepatitis B virus and primary hepatocellular carcinoma: Family studies in Korea
✍ Hie-Won L. Hann; Chung Yong Kim; W. Thomas London; Pamela Whitford; Baruch S. Bl πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 French βš– 457 KB

## Abstract Chronic infection with hepatitis B virus (HBV) is closely associated with the etio‐pathogenesis of primary hepatocellular carcinoma (PHC). It has been proposed that infection with HBV early in life, frequently transmited by an HBV‐carrier mother, leads to persistent infection with HBV,

Primary hepatocellular carcinoma and hep
Primary hepatocellular carcinoma and hepatitis B infection during childhood
✍ Tzee Chung Wu; Myron J. Tong; Betau Hwang; Shou-Dong Lee; Mu Mei Hu πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 380 KB

Twenty pediatric patients with primary hepatocellular carcinoma in Taiwan were tested for HBsAg, and all were found to be positive. The youngest case was 8 months of age, five cases occurred between 9 and 10 years of age, and 14 cases occurred between 11 and 16 years of age. The serum a-fetoprotein

Hepatitis-B virus infection in black chi
Hepatitis-B virus infection in black children with hepatocellular carcinoma
✍ Professor M.C. Kew; J. Hodkinson; A.C. Paterson; E. Song πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 484 KB

## Abstract The hepatitis B virus (HBV) status of six unselected South African Black children, aged 10 to 16 years, with hepatocellular carcinoma (HCC) was investigated. The characteristics of the tumor were similar to those seen in Black adults. Hepatitis B surface antigen and antibody to the core

Hepatitis B virus (HBV)-DNA-positive hep
Hepatitis B virus (HBV)-DNA-positive hepatocellular carcinoma following hepatitis B virus infection in a child
✍ Dr. R. Giacchino; P. Pontisso; C. Navone; A. Alberti; G. Dini; F. Facco; B. Cira πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 270 KB

Integrated hepatitis B virus (HBV) DNA sequences were found in neoplastic liver tissue of a hepatitis B surface antigen (HBsAg)-negative child who had previously suffered from HBsAg-positive chronic active hepatitis and was anti-HBs and antihepatitis B core (HBc) positive at the time of tumor develo