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Primary diffuse malignant peritoneal mesothelioma: Case report and update of therapy

โœ Scribed by Diego Piazza; Francesco Caruso; Stefano Scaringi; Marcello Ferrara; Fiorenza Latteri; Danila Dell'Erba

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
404 KB
Volume
75
Category
Article
ISSN
0022-4790

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โœฆ Synopsis

Background and Objectives: Primary Diffuse Malignant Peritoneal Mesothelioma is a rare disease, with an incidence of 2.2 cases in 1.000.000 in the USA. It occupies 10% of all mesotheliomas referred in literature. Methods: We describe a case of diffuse malignant peritoneal mesothelioma arising in a 54-year-old woman who presented a small bowel occlusion. A middle line laparotomy was done; multiple biopsies and an ileostomy were performed. There was not a history of exposure to asbestos. Histologic diagnosis was based on light microscopy, histochemistry, and immunohistochemistry. Results: Patient had no further treatment because of her poor general conditions. She died 4 months later. Conclusions: Update of treatment is briefly described with particular attention to multimodality approach (surgery, chemotherapy, radiotherapy) and other new therapeutic options (iperthermochemotherapy, immunotherapy, gene therapy), currently in clinical trials.

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