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Primary carcinoid tumor of the liver: Report of four resected cases including one with gastrin production

✍ Scribed by Krishnamurthy, Shanta C.; Dutta, Vibha; Pai, Sanjay A.; Kane, Shubhada V.; Jagannath, P.; Desouza, Luzito J.; Deshpande, Ramakant; Desai, Prafulla B.


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
467 KB
Volume
62
Category
Article
ISSN
0022-4790

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✦ Synopsis


Four cases of primary hepatic carcinoid were identified during a retrospective study of liver resections for primary tumor. The cases included two adult males, one adult female, and a 9-year-old boy in whom gastrin levels were documented. The estimation of gastrin levels was prompted by symptoms suggestive of acid-peptic disease. One patient died postoperatively. The other three are alive and well at 3 years, 2 years, and at 1 year, respectively, after surgery, outcomes distinctly different from hepatocellular carcinomas. Diagnostic difficulties may be experienced in histologic assessment, and this may require recourse to immunohistochemistry and electron microscopy. Long-term follow-up and careful exclusion of a possible primary elsewhere are necessary for establishing the primary nature of liver carcinoids.